Irene Loizidou Nicolaidou has studied Law at the National and Kapodistrian University of Athens and graduated in 1999. She also has a Degree in Journalism. In 2007, she was awarded a Masters Degree in Business Administration (MBA) by the Cyprus International Institute of Management (CIIM). She is an Accredited Mediator of CEDR (Center for Effective Dispute Resolution). She was a Member of the Cyprus Bar Association and she practiced Law from 2000 until 2015, when she was appointed as Commissioner for Personal Data Protection of Cyprus.

In 2001, Irene was elected as Member of Engomi, Nicosia Municipal Council for three consecutive (five year) terms. In this capacity, she served as a Permanent Member of the Cyprus Municipal Councils’ Association, to the Congress of the Local and Regional Authorities of Council of Europe and as Vice President of the Monitoring Committee of the Congress from 2007, till she assumed the position of the Commissioner.  

As of September 2015, Irene is the Commissioner for Personal Data Protection and as of December 2020, she also acts as Information Commissioner. Since May 25, 2023, Irene is the Deputy Chair of the European Data Protection Board.